Print This Post Print This Post

Neurological Disease: Advice You Won’t Hear From Your Conventional Doctor

Written by Wellness Club on July 13, 2011 – 2:06 pm -

Neurological Disease: Advice You Won’t Hear From Your Conventional Doctor

 

By Dr. Dana Myatt

 

Treating Neurological Disease (M.S., Parkinson’s, ALS)

 

Recently I’ve had a lot of people asking about what to do for neurological conditions. Here’s my best “general” advice. (I can give more “specific” advice when I work with someone personally. Please read on).

You’ll NEVER hear any of this from your conventional medical doctor, for at least two reasons.

First, there are no known cures for neurological diseases in conventional medicine. In fact, even our symptomatic treatments are fairly lame.

Secondly, when a doctor does have information about a “non standard” (read that: “not conventional medicine”) approach, he or she could lose their medical license by telling you about it.

So don’t be disappointed if your conventional medical doctor, no matter how good or well-respected, doesn’t have much hope to offer. That’s conventional medicine.

What I Would Immediately Do If I Were Diagnosed With a Neurological Disease

If I found out tomorrow that I had a neurological disease, here are the steps I would take right away:

  1. Have several non-conventional laboratory studies performed, including:
    1. Hair Mineral Analysis: to evaluate for heavy and toxic metal poisoning. This applies to ALL neuro conditions.
    2. Food allergy testing: to rule out immune responses to food allergies as a cause for symptoms. (This is especially important in MS).
    3. Neurotransmitter (NT) Testing: to look at neurotransmitter hormone levels. (This applies to all neuro conditions but is especially important in Parkinson’s, where a dopamine deficiency is often seen).
  2. Holistic dental evaluation, with removal of all dissimilar dental metals.
    NOTE: VERY FEW holistic dentist really understand this, and even fewer conventional dentists “get it.” If you have it done incorrectly (as most “holistic” dentists are likely to do), it can cause more harm than good. Please don’t have any dental work done until you have talked to me first!
    How important do I think this is? I have already had all metal removed from my mouth except for one full-gold crown. It is that important. If I hadn’t already had this done, I would get it done immediately, after I confirmed the skill and knowledge level of the attending dentist.
  3. Diet changes:
    1. Eliminate all food allergies (see above, laboratory testing).
    2. The Myatt Diet: low carbohydrate, high Omega-3 fatty acids. This is THE healthiest way to eat, proven by long-lived populations. This plus elimination of known food allergies relieves all dietary stress on the immune and nervous systems. Look for organic foods, too, since pesticide and herbicide toxicity is associated with neurological disease. Additional fish oil should be supplemented in those not regularly consuming wild Alaskan salmon and grass-fed beef. Ketogenic diets such as The Myatt Diet have proven useful for Parkinson’s, ALS and inoperable brain cancers. The diet switches the brain from using sugar for fuel to using ketones for fuel, and this “metabolic switch” is associated with fewer tremors and better movement.
    3. Discontinue ALL soy products, and milk (cow’s milk / dairy variety),
  4. Nutritional supplements: I’d make sure that I didn’t have a single nutrient deficiency known to cause or exacerbate a neurological disease. Here are the known connection.
    1. Parkinson’s: deficiencies of folic acid, B12, vitamins C, E and D are highly associated. Besides getting out in the sun, I’d be taking daily Maxi Multi’s to have achieve the recommended doses of these vitamins. CoQ10 has also shown to slow progression of the disease, but the dose needs to be higher, 1,200mg per day. Avoid iron, as iron overload can cause Parkinson’s and a number of other diseases. (You should be tested for iron overload with a serum ferritin test).
    2. M.S.: vitamin D deficiency is associated MS. Lower levels of calcium, magnesium, vitamin E and other antioxidant nutrients have been observed in MS patients and appear to slow progression of the disease. Vitamin B1 and niacin have proven to be useful. As with Parkinson’s, I’d get more sunshine and take Maxi Multis to have all of these nutrient bases covered.
    3. Amyotrophic Lateral Sclerosis (ALS): Hi B12, gamma-E tocopherol, zinc, copper, selenium, CoQ10, Alpha-lipoic acid, Acetyl-L-carnitine, creatine, curcumin, DHEA, glutathion, green tea, N-acetylcysteine, grape seed extract (pycnogenol), resveratrol (grape skin extract) and vinpocetin. These vitamins, minerals amino acids and trace minerals have all been shown to alter various aspects of the disease.
  5. Schedule a telephone consultation with ME, or someone just like me. A physician who is not limited by conventional medical techniques (but is still trained in them and can prescribe all conventional tests and drugs) will be your best bet for obtaining a full and complete evaluation of the causes of neurological disease. The sooner this is done, the better the chance for a more full and complete recovery.

I hope this provides help and comfort to the numerous health-seekers who contacted me recently about neurological concerns!

 

References:

  1. Journal of Neurochemistry January 2002;80:101-110
  2. Neurology March 22, 2005;64(6):1047-1051
  3. Journal Clinical Toxicology 2003;41(1):67-70
  4. American Journal Epidemiology March 1, 2003;157(5):409-14
  5. Malosse D, Perron H, Sasco A, Seigneurin JM. Correlation between milk and dairy product consumption and multiple sclerosis prevalence: a worldwide study. Neuroepidemiology 1992;11:304–12.
  6. Swank RL. Multiple sclerosis: fat-oil relationship. Nutrition 1991;7:368–76.
  7. Esparza ML, Saski S, Kesteloot H. Nutrition, latitude, and multiple sclerosis mortality: an ecologic study. Am J Epidemiol 1995;142:733–7.
  8. Dines KC, Powell HC. Mast cell interactions with the nervous system: relationship to mechanisms of disease. J Neuropathol Exp Neurol 1997;56:627–40.
  9. Stern EI. The intraspinal injection of vitamin B1 for the relief of intractable pain, and for inflammatory and degenerative diseases of the central nervous system. Am J Surg 1938;34:495.
  10. Moore MT. Treatment of multiple sclerosis with nicotinic acid and vitamin B1. Arch Int Med 1940;65:18.
  11. Fahn S. A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinson’s disease. Ann Neurol 1992;32:S128–32.
  12. Shoulson I. DATATOP: a decade of neuroprotective inquiry. Parkinson Study Group. Deprenyl And Tocopherol Antioxidative Therapy Of Parkinsonism. Ann Neurol 1998;44:S160–6.
  13. Fahn S. A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinson’s disease. Ann Neurol 1992;32:S128–32.
  14. Dexter DT, Carayon A, Javoy-Agid F, et al. Alterations in the levels of iron, ferritin and other trace metals in Parkinson’s disease and other neurodegenerative diseases affecting the basal ganglia. Brain 1991;114:1953–75.
  15. Dexter DT, Carayon A, Javoy-Agid F, et al. Alterations in the levels of iron, ferritin and other trace metals in Parkinson’s disease and other neurodegenerative diseases affecting the basal ganglia. Brain 1991;114:1953–75.
  16. Pall HS, Williams AC, Blake DR, et al. Raised cerebrospinal fluid copper concentration in Parkinson’s disease. Lancet 1987;2(8553):238–41.
  17. Nutritional factors in the pathogenesis and therapy of respiratory insufficiency in neuromuscular diseases. Monaldi Arch Chest Dis. 1993;48(4):327–330.
  18. N-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis. Neuroreport. 2000;11(11):2491–2493.
  19. Effects of an inhibitor of poly(ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice. Exp Neurol. 2001b;168(2):419–424.
  20. Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation. J Neurochem. 2001a;77(2):383–390.
  21. Glutathione peroxidase in amyotrophic lateral sclerosis: the effects of selenium supplementation. J Environ Pathol Toxicol Oncol . 1998;17(3–4):325–329.
  22. Vitamin E intake and risk of amyotrophic lateral sclerosis. Ann Neurol . 2005;57(1):104–110.
  23. Coenzyme Q10 as a possible treatment for neurodegenerative diseases. Free Radic Res . 2002;36(4):455–460.
  24. Neurodegenerative memory disorders: a potential role of environmental toxins. Neurol Clin . 2005;23(2):485–521.
  25. Nutritional issues and supplements in amyotrophic lateral sclerosis and other neurodegenerative disorders. Curr Opin Clin Nutr Metab Care. 2002;5(6):631–643.
  26. Acetyl-L-carnitine and Alzheimer’s disease: pharmacological considerations beyond the cholinergic sphere. Ann N Y Acad Sci. 1993;695:324–326.
  27. Zinc metabolism in the brain: relevance to human neurodegenerative disorders. Neurobiol Dis. 1997;4(3–4):137–169.
  28. The role of excitotoxicity in neurodegenerative disease: implications for therapy. Pharmacol Ther. 1999;81(3):163–221.
  29. Protection by dietary zinc in ALS mutant G93A SOD transgenic mice. Neurosci Lett . 2005;379(1):42–46.
  30. Therapeutic efficacy of EGb761 ( Gingko biloba extract) in a transgenic mouse model of amyotrophic lateral sclerosis. J Mol Neurosci . 2001;17(1):89–96.
  31. High dose vitamin E therapy in amyotrophic lateral sclerosis as add-on therapy to riluzole: results of a placebo-controlled double-blind study. J Neural Transm . 2005;112(5):649–660.
  32. Amyotrophic lateral sclerosis and occupational heavy metal exposure: a case-control study. Neuroepidemiology . 1986;5(1):29–38 .
  33. Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Proc Natl Acad Sci U S A. 2002;99(4):1870–1875.
  34. Neuroprotective effect of green tea extract in experimental ischemia-reperfusion brain injury. Brain Res Bull. 2000;53(6):743–749.
  35. Kinetics of reduction of ferrylmyoglobin by (-)-epigallocatechin gallate and green tea extract. J Agric Food Chem. 2002;50(10):2998–3003.
  36. Effect of ultrahigh-dose methylcobalamin on compound muscle action potentials in amyotrophic lateral sclerosis: a double-blind controlled study. Muscle Nerve . 1998;21(12):1775–1778.
  37. Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity. Proc Natl Acad Sci U S A. 1998;95(4):1852–1857.
  38. Antioxidants and herbal extracts protect HT-4 neuronal cells against glutamate-induced cytotoxicity. Free Radic Res. 2000;32(2):115–124.
  39. Evidence for the stimulatory effect of resveratrol on Ca(2+)- activated K+ current in vascular endothelial cells. Cardiovasc Res 2000;45(4):1035–1045.
  40. Lim GP, Chu T, et al. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci. 2001;21(21):8370–8377.
  41. Curcumin, a molecule that inhibits the Ca2+-ATPase of sarcoplasmic reticulum but increases the rate of accumulation of Ca2+. J Biol Chem. 2001;276(50):46905–46911.
  42. Randomized, double-blind, controlled trial of acetylcysteine in amyotrophic lateral sclerosis. Arch Neurol. 1995;52(6):559–564.
  43. Mano Y, Takayanagi T, et al. [Amyotrophic lateral sclerosis and mercury—preliminary report]. Rinsho Shinkeigaku. 1990;30(11):1275–1277.
  44. Neuroprotection by dehydroepiandrosterone-sulfate: role of an NFkappaB-like factor. Neuroreport. 1998;9(4):759–763.
  45. Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc Natl Acad Sci U S A . 1998;95(15):8892–8897.
  46. Effects of creatine supplementation on exercise performance and muscular strength in amyotrophic lateral sclerosis: preliminary results. J Neurol Sci. 2001;191(1–2):139–144.
  47. Mitochondrial involvement in amyotrophic lateral sclerosis. Neurochem Int. 2002;40(6):543–551.
  48. Amyotrophic lateral sclerosis: toxins and environment. Amyotroph Lateral Scler Other Motor Neuron Disord . 2000;1(4):235–250.
  49. Prolonged pretreatment with alpha-lipoic acid protects cultured neurons against hypoxic, glutamate-, or iron-induced injury. J Cereb Blood Flow Metab. 1995;15(4):624–630.
  50. Biochemical characterization of plasma in amyotrophic lateral sclerosis: amino acid and protein composition. Amyotoph Lateral Scler Other Motor Neuron Disord . 2005;6(2):104–110.
  51. Clinical pharmacology of the dietary supplement creatine monohydrate. Pharmacol Rev. 2001;53(2):161–176.
  52. Antioxidant therapy in ALS. Amyotroph Lateral Scler Other Motor Neuron Disord. 2000;1(Suppl 4):5–12; discussion 13–15.
  53. An increase of oxidized coenzyme Q-10 occurs in the plasma of sporadic ALS patients. J Neurol Sci . 2005;228(1):49–53.
  54. The slippage of the Ca2+ pump and its control by anions and curcumin in skeletal and cardiac sarcoplasmic reticulum. J Biol Chem. 2002;277(16):13900–13906.
  55. Potential for creatine and other therapies targeting cellular energy dysfunction in neurological disorders. Ann Neurol. 2001;49(5):561–574.
  56. A 1-year controlled trial of acetyl-1 -carnitine in early-onset AD. Neurology. 2000;55(6):805–810.
  57. Effect of creatine supplementation on metabolite levels in ALS motor cortices. Exp Neurol. 2001;172(2):377–382.
  58. Vinpocetine-enhanced stimulation of calcium-activated potassium currents in rat pituitary GH3 cells. Biochem Pharmacol. 2001;61(7):877–892.
  59. Alpha lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells. Faseb J . 2001;15(13): 2423–2432.
Print This Post Print This Post
SocialTwist Tell-a-Friend

Posted in Mental Health, Senior Health | No Comments »

Sorry, comments for this entry are closed at this time.


Disclaimer: These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. No information on this website is intended as personal medical advice and should not take the place of a doctor's care.