Category: Mental Health

  • Is Kavinace Safe?

    By Nurse Mark

     

    We often get questions asking whether this or that or another supplement is “safe.”

     

    These are really tough questions: Safe for who? And in what dose? And whose brand? And what other health conditions, drugs, or supplements are involved?

    Even natural supplements can cause problems if overused or misused…

    Kavinace is one of our more popular supplements, for very good reason – it is an excellent sleep aid. We have written often about Kavinace – here is one of our recent articles: Kavinace or the Lunesta Moth – You Decide.

    Kavinace is a proprietary blend of taurine and phenibut.

    Phenibut (β-phenyl-γ-aminobutyric acid) is a derivative of the naturally occurring inhibitory neurotransmitter GABA. It tends to function as a CNS (Central Nervous System) depressant – which is part of the reason it is so effective as a sleep aid. It has also been shown to increase dopamine levels – and dopamine is considered to be one of the “feel-good” neurotransmitters.

    We have never encountered legitimate reports of  persons becoming physically addicted to phenibut or to Kavinace – though it is possible to become psychologically addicted to anything, especially if that thing is misused or overused. There are anecdotal reports of people using very large doses of phenibut on a regular basis (it is often used by people who feel socially awkward or anxious) who have found that very large repeated doses of pure phenibut have caused addictive effects – that stopping the very high doses led to feelings of anxiety returning.

    How to avoid any danger of tolerance or addiction? Easy – never use more than the recommended amount!

    Here is a recent question, and Dr. Myatt’s reply:

    Subject: Is kavinace safe?
    Message: Hello, I had a neurotransmitter urine test and it was suggested I use Kavinace. I am apprehension of the Phenibut causing addiction. I am sixty four and having horrible panic and do not want to use pharmaceuticals. Is Kavinace safe?
    Thank you so much, Peggi

     

    Hi Peggi:

    Sorry for your travails. Panic attacks are no fun, although on a positive note, I’ve never lost a patient to a panic attack. Remind yourself of this when you are in the throes.

    Use of a neurotransmitter test before starting neurotransmitter treatment has largely been discredited by actual research, although several companies including Neuro Science (makers of Kavinace) still promote this. One could just have easily suggested Kavinace to you based on your complaint of panic attacks.

    Phenibut is effective and as far as I can see, safe when used moderately. I have not seen dependence in anyone although I know this is a concern.

    Please keep in mind that panic attacks are not caused by a phenibut deficiency! Which means, even if it helps, it doesn’t get to the root of the problem.

    The most common causes of panic attacks include hormone imbalances or deficiencies, neurotransmitter imbalances and — the big one — unstable blood sugar levels. Do you wake up in the middle of the night, say between midnight and 3 a.m., filled with anxiety?

    I would like to review the "rule out" list with you and we can do this on a brief phone consult. Here’s the link on how to schedule: https://www.drmyattswellnessclub.com/BriefConsults.htm

    Panic attacks are correctable but drugs and even natural substances, though they may provide relief, don’t really cure the problem.

    Whatever you do, I’m wishing you a complete resolution from this most annoying problem.

    In Health,
    Dr. Myatt

  • The Safe, Proven Memory Drug Your Doctor Can’t Prescribe

    By Nurse Mark

     

    Doctors in more than 70 countries routinely prescribe this as a drug for head trauma, stroke, neurogenerative disease, glaucoma and more – but your US doctor can’t write you a prescription for it. Why? Because it’s not an FDA “approved drug.”

    Medical studies worldwide, including many studies conducted in the USA, have proven the worth of this drug over and over for a variety of neurological (brain, thought, and memory) conditions – but for all our progress and medical superiority here at home, you cannot get it as a drug here.

    Why is this a Big Deal?

    Let’s look at a few things that doctors worldwide prescribe this amazing drug for:

    In Japan and in Europe it is approved for treating head trauma, stroke, and neurodegenerative diseases. European and Japanese doctors also prescribe it to improve recovery following an ischemic stroke (stoke caused by blood clot), as they have found that it reduces the damage caused by these strokes and improves healing.

    In fact, a respected clinical neurological researcher at the University Hospital of Copenhagen stated in a recent paper:

    [this] is the only drug that in a number of different clinical stroke trials continuously had some neuroprotective benefit.

    So, this drug (that’s not a drug in the USA) is the king of drugs for ischemic stroke treatment – and ischemic (blood clot) strokes are by far the most common type.

    What else is it good for?

    Spanish researchers have found that it is valuable in the treatment of memory disorders. It has been found effective in improving memory retention, and in lab studies has been shown to be protective against the ravages of Alzheimer’s Disease.

    Researchers at the EuroEspes Biomedical Research Center in Spain make the following statement:

    Based on these results, it was concluded that [it] exerts antiapoptotic, neuroprotective and antiamnesic effects in conditions of neurodegeneration induced by A beta 4 plus hypoperfusion.

    In plain English? It prevents the death of stressed brain cells, protects other brain cells from stress and damage, and helps to prevent the loss of memories (amnesia) that are a part of Alzheimer’s disease.

    The “Eyes” have it…

    Vision and brain and nerve function are all inter-dependant, and European researchers have embraced this drug as a treatment for both glaucoma and for ischemic optic neuropathy – two leading causes of blindness.

    An Italian clinical researcher at the G.B. Bietti Eye Foundation-IRCCS in Rome wrote of his findings:

    Glaucoma:

    The extension of {this drug] treatment up to a period of 8 years lead to the stabilization or improvement of the glaucomatous visual dysfunction. These results suggest potential neuroprotective effects of [the drug] in the glaucomatous disease.

    Non-arteritic ischemic neuropathy (NION):

    At the end of treatment (days 60 and 240), T-NION patients showed improvement … Conclusions: Our results suggest a beneficial effect of oral Citicoline in NION.

    Millions of Americans facing devastating vision loss and blindness could be benefiting from it, but tragically this is not a drug that their conventional doctors can prescribe.

    What do overeating and cocaine addiction have in common?

    Cocaine addiction is known to be associated with depleted dopamine levels in the brain. In cocaine addiction this drug has been found to increase brain dopamine levels and to reduce cocaine cravings.

    In general this drug increases the brains responses to the stimulus resulting from eating and by doing so results in improved feelings of satiety and decreased appetite.

    Researchers at our own Harvard Medical School studied this substance in cocaine-dependant volunteers and noted:

    Subjects did not experience any side effects and [the] treatment was associated with decreases in self-reported mood states associated with cocaine craving. These preliminary data are encouraging and suggest that [this substance] warrants further study as a promising potential treatment for cocaine abuse and dependence that is devoid of side effects.

    Helping to reduce the cravings for an addictive drug, and no side effects – isn’t that what our “War On Drugs” should be all about?

    And with regard to appetite… again from the experts at Harvard:

    RESULTS: After 6 weeks, there was no significant change in weight status, although significant declines in appetite ratings were observed for the 2,000 mg/day group. The higher dose group also showed significant increases in functional brain responses to food stimuli within the amygdala, insula, and lateral orbitofrontal cortex. Increased activation in these regions correlated with declines in appetite ratings.

    DISCUSSION: These preliminary findings suggest a potential usefulness of [this substance] in modulating appetite, but further research is warranted.

    Of course “further research is warranted” – this is a coded message to Big Pharma to say “this stuff works, and you had better fund us to either figure out how you can profit with it or to find some way to bury it so your patented drugs won’t have any competition!”

    Imagine if there was a drug that your doctor could prescribe that would allow you to go about your day with your appetite under control – a drug without dangerous side-effects. Well, there is – but not in this country!

    So, given the huge amount of research showing positive effects of this drug on a wide variety of neurological conditions, and it’s lack of any significant side effects, is there any wonder that doctors around the world routinely write prescriptions for it?

    In much of South America a doctor would prescribe Somazina; in Austria the script would be for Startonyl; your Japanese doctor might prescribe it as Tesi Cholin, in China, it is known as Ying Di Te.

    But in the United States? There is no name for it as a drug – no drug company markets it as a drug in the US. That means no doctor can prescribe the Sandoz drug Onquevit – even though it is widely available to doctors and patients in Mexico. It is not “approved” as a drug by the FDA and thus your doctor can’t prescribe it, your insurance company won’t pay for it, and if your doctor did try to ‘color outside the lines” and prescribe it for you he could face the wrath of the doctor licensing organizations and Big Pharma…

    But all is not lost – there is a “loophole.” This amazing substance, considered to be safe and approved as a “drug” in so many other countries is available outside of the conventional medical system here as a “Dietary Supplement.”

    Cognizin is a nutritional supplement that is the same as “drugs” that are prescribed in over 70 other countries. It is the same strength, the same purity, and works exactly the same when used in the same doses.

    Even though your conventional doctor can’t prescribe it as a drug and your insurance company is not likely to pay for it, it’s not expensive when one considers all of it’s benefits.

    It’s not an “overnight wonder” like many of the offerings of Big Pharma – it takes time, like weeks or months to work. But it also doesn’t have the nasty and noticeable side-effects that so many people have come to expect from many of their “FDA Approved” drugs.

    We are receiving anecdotal reports of it’s good effects from our patients and customers: better performance with the morning crossword puzzle, fewer incidents of lost car keys (and lost cars), less frequent stumbling for words that are “on the tip of the tongue” and reports from family members noticing positive changes in thought and memory.

    A suggested starting regimen would be 2000 mg per day for the first month to 6 weeks, and then dropping to half of that for maintenance. That translates to 4 capsules of Cognizin twice daily to start and then two capsules twice daily after that.

    Given the strength of the research that clearly demonstrates the benefits of this “brain drug” that-is-not-a-drug, we believe it is definitely worth a try.

    Learn More About Cognizin – The Miracle Memory Drug Your Doctor Can’t Prescribe

     

    References:

    Warach, S; et al. (November 2000). "Effect of citicoline on ischemic lesions as measured by diffusion-weighted magnetic resonance imaging. Citicoline 010 Investigators.". Annals of neurology  http://www.ncbi.nlm.nih.gov/pubmed/11079534

    Overgaard, K (2014). "The effects of citicoline on acute ischemic stroke: a review.". Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association http://www.ncbi.nlm.nih.gov/pubmed/24739589

    Alvarez, XA; et al. (October 1999). "Citicoline protects hippocampal neurons against apoptosis induced by brain beta-amyloid deposits plus cerebral hypoperfusion in rats.". Methods and findings in experimental and clinical pharmacology. http://www.ncbi.nlm.nih.gov/pubmed/10599052

    Parisi, V; et al. (2008). "Evidence of the neuroprotective role of citicoline in glaucoma patients.". Progress in brain research http://www.ncbi.nlm.nih.gov/pubmed/18929133

    Parisi, V.; et al. (1 May 2008). "Cytidine-5′-diphosphocholine (Citicoline): a pilot study in patients with non-arteritic ischaemic optic neuropathy". European Journal of Neurology http://onlinelibrary.wiley.com/doi/10.1111/j.1468-1331.2008.02099.x/abstract

    Renshaw, PF; et al. (February 1999). "Short-term treatment with citicoline (CDP-choline) attenuates some measures of craving in cocaine-dependent subjects: a preliminary report.". Psychopharmacology http://www.ncbi.nlm.nih.gov/pubmed/10102764

    Killgore, WD; et al. (January 2010). "Citicoline affects appetite and cortico-limbic responses to images of high-calorie foods.". The International Journal of Eating Disorder. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378241/

  • Robin Williams: A Tragic Death That Might Have Been Prevented

    By Nurse Mark

     

    The tragic death of comedian Robin Williams underscores the importance of maintaining a healthy neurotransmitters (brain hormones). Although Williams’ death was reportedly caused by hanging (suicide), Dr. Myatt and Nurse Mark know differently. The facts of Williams’ life and death support our thesis — that Robin Williams suffered from a severe but quite likely correctable neurotransmitter imbalance. Here are the facts of the case:

     

    Neurotransmitters (NT’s) are chemicals that affect the brain in addition to numerous other physical functions. Think of NT’s as "brain hormones," because they are. A dopamine deficiency leads to depression and is also the primary problem in Parkinson’s. Alcohol and cocaine further deplete dopamine; Williams was known to have a substance abuse problem with both. Prescription "head meds" (SSRI’s, SNRI’s and other anti-depressants) further deplete dopamine.

     

    Dopamine is an important neurotransmitter because it regulates physical actions such as movement. It is also a "feel good" brain hormone. When it’s deficient, either because we don’t have enough of the chemical or because our damaged neurons require higher-than-normal amounts to function normally, we feel bad – typically depressed, and movement suffers – Parkinson’s disease.

     

    A primary cause of dopamine deficiency is lack of appropriate precursor amino acids in the system. Nutrients involved in the production of dopamine may also be deficient. Alcohol, cocaine and even prescription anti-depressants stimulate and then deplete dopamine stores.

     

    Poor Robin was in a "perfect storm" for the travails that led him to commit suicide.

     

    The recent tragic death by suicide of Robin Williams has touched us all.

     

    Robin was a comedic genius – but like many who have the gift of genius, Robin had a dark side as well.

    It is well-known that Robin Williams struggled with drug and alcohol use for many years, and wrestled with the demons of depression.

    His widow has revealed that he had recently been diagnosed with early stage Parkinson’s disease.

    It is easy to say, as some have suggested, that in his sixties, still struggling with alcohol and drug problems, and suddenly given a bleak diagnosis of a debilitating neurological disease, the demons of his depression became too powerful and he sought relief in suicide.

    It is easy to say that, but we here at The Wellness Club don’t believe it.

    We believe that there is more to it than simply the despair of addiction, depression, and illness and that while Robin Williams may have succumbed it need not have happened. The story could have had a much different ending, and perhaps Robin’s great legacy will be a life-saving change in the way we look at the relationship between drugs and alcohol and depression and neurological diseases such as Parkinson’s.

    Consider these points:

    Dopamine is essential to much of our brains workings – but most importantly it is the “feel-good” neurotransmitter. When we have plenty of it we feel good. When we are deficient, either because we don’t have enough of the chemical or because our neurons don’t use it right, we feel bad – depressed.

    Chronic alcohol use or abuse – alcoholism – depletes the brain chemical dopamine.

    Drug abuse stimulates dopamine release. When dopamine remains in the synapse longer, it is degraded.

    Here is a quote from a noted expert in brain chemistry, Dr. Marty Hinz:

    All drugs of abuse target the brain’s reward system by increasing dopamine. Dopamine is a neurotransmitter present in regions of the brain that regulate movement, emotion, cognition, motivation and feelings of pleasure. The overstimulation of this system, which rewards our natural behaviors, produces the euphoric effects sought by people who abuse drugs and teaches them to repeat the behavior. When some drugs of abuse are taken, they can release two to 10 times the amount of dopamine that natural rewards do. The effect of such a powerful reward strongly motivates people to take drugs again and again.

    So here is a possible scenario for someone like Robin Williams:

    Feeling a little “down” (depressed) as everyone does at some time or other, Robin doesn’t know that his dopamine levels are not what they might be. He just knows that he feels down. “Have a drink – that’ll cheer you up!” says a well-meaning friend, and Robin does, and the friend was right – he felt better. That worked so well in fact that the next time he felt a bit down he had another drink – and felt better. And the next time, and the next time…

    After a while though, the alcohol is depleting his stores of dopamine and there just isn’t enough of the “feel-good” chemical available even with a few drinks to “help.” Not even with a lot of drinks…

    So, another well-meaning “friend” says “Here – try a little cocaine – it’ll make you feel great!” Robin tries it and his friend was right – he felt great! On top of the world! He suddenly flooded his brain so much dopamine that he felt better than he had for a long time – and able to face whatever problems were bedeviling him. Who wouldn’t want to experience that, over and over again…

    Meanwhile, Robin might be concerned enough about feeling depressed that he would see a doctor. The doctor would most certainly prescribe antidepressant drugs. Unfortunately, antidepressant drugs also deplete dopamine. Robin might have felt better briefly, but the antidepressant drugs don’t work well for long – and he would likely have entered into an endless search for “the right drug” – the one that would bring him some long-term relief to the depression that was making life a misery. But in the end, all the antidepressant drugs do is further damage neurotransmitter function – especially dopamine.

    But our human bodies are tough, adaptable, and forgiving organisms. All these insults to our neurotransmitters – especially to that important feel-good neurotransmitter dopamine – we “deal with” and carry on, compensating, adapting, managing. Like a boxer who becomes inured to being hit, bruised, concussed, and worse, or a rodeo cowboy whose profession provides him with more trauma, bruises and broken bones than anyone should have to bear, people battering their neurotransmitters with alcohol, recreational drugs, and prescription head-meds ride the ups and downs of neurotransmitter depletion and they adapt and they manage – often by self-medicating with more alcohol and drugs. For a while.

    But like the boxer or rodeo cowboy, there comes a time when there just aren’t any more reserves.

    There comes a time when the neurotransmitters – like dopamine – just aren’t there any more, or what is left isn’t working.

    They are tapped out – empty.

    Parkinson’s disease is a condition in which dopamine, which in addition to being the “feel-good” neurotransmitter is also a neurotransmitter that is important to regulating movement, is either not there or the nerve cells are unable to use it properly.

    For someone who has spent many years abusing their neurotransmitters with alcohol, recreational drugs, and prescription psychiatric drugs like SSRI’s, “early Parkinson’s” may be their warning that they have reached the end of their rope when it comes to their ability to “bounce back.”

    Many people regard affliction with Parkinson’s disease to be only slightly less devastating than Alzheimer’s disease. To be given a diagnosis of “early Parkinson’s” conjures up visions of shaking, shuffling, helpless people, ultimately unable to speak or care for themselves. I remember one patient who said to me “Give me a clean death – not that!” when we were discussing his recent diagnosis of Parkinson’s. I found myself agreeing with him.

    Robin Williams knew about Parkinson’s, and about the mainstay drug used to treat it – L-dopa; a precursor to the neurotransmitters dopamine, norepinephrine, and epinephrine or adrenaline – our catecholamines. As a skilled actor who had a starring role in the film “Awakenings” (1990) he would have researched his character and the drug and he would have known that while L-dopa has a miraculous effect on Parkinson’s and other such movement diseases, the side effects are serious and the benefits are not all that long-lasting. Sufferers are given a reprieve, not a cure, and when the drug stops working the disease symptoms return with a vengeance.

    Running out of dopamine is a bad business, and Parkinson’s is a very visible, tangible result of years of abusing one’s dopamine stores.

    But must this always be what happens? Is there no hope for someone who becomes depressed and self medicates to feel better? Must the results always be this tragic?

    No.

    Our bodies, and our brains, are very well-designed organisms; resilient and hardy. Things don’t usually “go wrong” for no good reason. When things do “go wrong” it is often an outside influence – a stressor – to our systems. Infection, injury, mental stress, can all precipitate unwanted changes to our finely balanced biology. So can the failure to provide our bodies with the nutrients needed to sustain and heal and grow.

    The neurochemicals that our brains rely on to function are made by our bodies from raw materials called amino acids – from proteins.

    When we deprive our bodies of the essential amino acids required for the manufacture of vital hormones and neurotransmitters we can compensate for a while – but not forever. We need to begin to supply these essential amino acids in generous quantities or we set ourselves up for serious problems.

    The standard answer of conventional doctors for problems such as those experienced by Robin Williams is to prescribe drugs. Those drugs either hide the symptoms or, in the case of SSRI drugs, make the few remaining supplies of neurochemicals work a little better for a while. But as Robin discovered, not for a long while. Like the drug L-dopa for Parkinson’s sufferers, the helpful effects of antidepressant drugs wear off all too soon and the symptoms, those dark demons of depression and despondency, return with a vengeance to torment the sufferer.

    A better approach is to ensure that the person has plentiful supplies of amino acids for his (or her) body to work with in creating vital neurotransmitters such as dopamine. If the body is able to make plentiful dopamine – the “feel-good” neurotransmitter – then there is less need, less desire for the person to seek the dopamine rush that comes from alcohol or drugs. Many cases of “addiction” can be “cured” by careful replenishment of amino acids in the diet.

    Although neurotransmitter balancing or repletion is best accomplished through natural means, it is NOT a do-it-yourself project. There are too many intricacies best managed by a natural physician who is highly trained in NT restoration. Primary treatment for these brain-hormone disorders include diet modification, supplementation and other lifestyle interventions. This is not a theory; the statistics for long-term treatment of Parkinson’s (dopamine depletion), depression and addiction show that these are are known to be little-helped by drugs while natural methods of neurotransmitter support have much higher success rates.

    Had we only known, we could have helped.

    Godspeed Robin Williams – you are loved and you are missed. If your untimely passing spurs even one person in similar circumstance to seek natural help then your death will not have been in vain.

    If you, or someone you care for is experiencing depression or battling addiction PLEASE, seek the help of a doctor qualified to test and replete neurotransmitters naturally.

    Q. Which comes first: depression then neurotransmitter depletion, or is it neurotransmitter depletion then depression?

    A. It doesn’t matter – all that really matters is that when neurotransmitters are plentifully replenished the demons of depression and addiction seem to go away and the sunny days of life return.

    PLEASE SEEK HELP – a Brief Telephone Consultation with Dr. Myatt is the easy way to get started.

  • Memory Tests: What’s Real And What’s Phony Baloney

    By Nurse Mark

     

    There is a lot of junk floating around the internet…

    And sooner or later, if it is in any way related to health, someone forwards it to us with the question “What do you think of this? Is it of any value? Is it something that you are aware of?”

    And so it is with the so-called “Alzheimer’s Eye Test” that makes the rounds of the internet from time to time.

    The basic premise of the “test” is that one reads a sentence and then quickly counts the number of letters “F” contained in that sentence.

    Here is the sentence: FINISHED FILES ARE THE RESULT OF YEARS OF SCIENTIFIC STUDY COMBINED WITH THE EXPERIENCE OF YEARS.

    The email goes on to claim that it is normal to identify 3 of the letters “F”, and that to identify 4 is rare and to identify all 6 is “genius.”

    Hmmm…

    Modesty prevents me from chuckling at this aloud, since I promptly identified all 6 when I first saw this, years ago. Oops, was that immodest of me? Sorry…

    Now, this is a fun little brain teaser sort of thing, but what it has to do with Alzheimer’s I really don’t understand – and I certainly can’t imagine what it has to do with memory.

    The rationale given for the fact that many people don’t immediately see 3 of the letters “F” is that “The brain cannot process the word ‘of’.”

    But if that is true, why do we use the word so much in our speech and our written communications? I’ll bet my second paragraph in this article would look awfully silly if I hadn’t used the word ‘of’ several times…

    A more likely explanation is that many people mispronounce the word of ‘of’ slightly, as ‘uv’ and thus our brains are not as likely to “hear” the ‘F’ in the word ‘of’.

    So, while this is a fun little game for young and old alike, it is hardly a diagnostic tool for determining either memory loss or Alzheimer’s disease.

    Afraid of losing your marbles?

     

    Most of us are – probably even all of us (at least all of us that haven’t already lost our marbles…) and that is why this kind of internet junk, a brain teaser made out to be some sort of simple, objective “test” is so popular.

    But it’s not objective, and it’s not a test, and it’s not diagnostic.

    Here is something that is objective and diagnostic:

    The Ohio State University has developed what they call their S.A.G.E. Test – the The Self-Administered Gerocognitive Exam.

    The Self-Administered Gerocognitive Exam (SAGE) is designed to detect early signs of cognitive, memory or thinking impairments. It evaluates your thinking abilities and helps physicians to know how well your brain is working.

     

    While this is primarily intended for doctors and other medical health professionals to administer to their patients, it can also be downloaded and used by laypersons. By clicking on the “for physicians” link on the webpage you can access the scoring and interpretation instructions for the test. But beware – you can seriously invalidate the results of your test by reading through the scoring and interpretation instructions before doing the test – so don’t do it! Better yet, have someone else download the test and score it for you – just as if you were going to your doctor for this test.

    There are 4 versions of the test – and it does not matter which version you take. There are 4 versions so that it can be repeated as needed in order to assess progress or change.

    Of all the things I’ve lost, I miss my mind the most.

    Mark Twain

    So what can you do?

     

    A personal story: I recently wrote about the benefits of citicoline for brain health: The Amazing Brain Nutrient You Don’t Know About.

    My Dad is 89 years young and has complained of C.R.S. (Can’t Remember Stuff) for many years now.

    He read that article and asked why he wasn’t taking citicoline. I sent him a couple of bottles with instructions to take a higher amount for the first bottle and then to drop back to a maintenance dosage after that.

    Dad recently wrote to say that he had been taking the citicoline as directed:

    Just a few lines to let you know (as requested) the results from the twice daily dosage of Cognizin. I must confess that the only sign so far of any change in my long-standing inability to remember much of anything is an apparent increase in the speed with which I finish the newspaper’s daily crossword puzzle which accompanies my daily breakfast. I guess this must be a positive sign that the stuff is working,

    Yes, finishing the daily crossword more rapidly is a very definite and objective sign that there is memory improvement – since crossword puzzles are all about remembering words and associating them with clues!

    Clinical and laboratory research show citicoline supports memory function and healthy cognition and there is clinical evidence suggesting that citicoline can improve memory problems associated with aging. (1, 2)

    Further, according to pharmacology researchers:

    The other major indication of citicoline is for treatment of senile cognitive impairment, either secondary to degenerative diseases (e.g. Alzheimer disease) or to chronic cerebral vascular disease. In patients with chronic cerebral ischemia, citicoline improves scores in cognitive rating scales, while in patients with senile dementia of the Alzheimer type it stops the course of disease, and neuroendocrine, neuroimmunomodulatory, and neurophysiological benefits have been reported. (3)

     

     

    References:

    1.) Spiers PA et al. Citicoline improves verbal memory in aging. Arch Neurol. 996;53:441-48.

    2.) Alvarez XA et al. Citicoline improves memory performance in elderly subjects. Meth Find Exp Clin Pharmacol. 1997;19(3):201-10.

    3.) Secades JJ1, Lorenzo JL.. Citicoline: pharmacological and clinical review, 2006 update. Methods Find Exp Clin Pharmacol. 2006 Sep;28 Suppl B:1-56. http://www.ncbi.nlm.nih.gov/pubmed/17171187

  • Which Neurochemical Causes Depression?

    By Nurse Mark

     

    I remember some of the classes that we took in Nursing School vividly – and no wonder; they were lectures on subjects that were so dense and incomprehensible that we looked forward to them the way one might look forward to having dental work done without freezing. Neuroanatomy and the endocrine system were a couple of my most dreaded subjects – at that time my only hope of surviving and graduating as a Nurse was to memorize enough to pass the exams…

    Well, fast-forward thirty years, and I have come to make peace with these and other complicated subjects. That is not to say that I am any kind of expert, but rather that I understand that everyone struggles to understand these subjects about as much as I do.

    I actually kind of enjoy the endocrine system – it is the chemical computer of hormones that controls and regulates almost every function of our being.

    And neuroanatomy? Well, let’s just say that we have reached a peace since I know how to look stuff up when I need it…

    The point here is that even after 30 years of Nursing and being exposed to these two subjects frequently (even daily) they are still complicated – there is nothing simple about either of them even after all these years. How very, terribly complicated and confusing must they be for laypeople?

    It is no wonder that modern conventional medicine has done such a good job of making folks demand simple, one-pill solutions to medical problems.

    We get questions every day from people who are looking for simple answers to complicated subjects: “Which hormone is making me fat?” “What herb will cure my (insert complaint here)?” “Which neurochemical is responsible for depression?”

    Dave recently wrote us. I am guessing that he found some information of interest on our Neurotransmitter information pages.

    I tried to write Dave back, but his email was returned to me as “undeliverable” – so here is Dave’s question:

    Subject: neurotransmitter imbalance

    Message: If a person already has clinical depression does the loss of a loved one affect the same neurochemicals ? I was told it creates a deficit however in which neurochemicals ?

     

    And my answer to Dave:

     

    Hi Dave,

    First, please do not confuse depression with sadness. The loss of a loved one is tragic and can be a terrible sadness, but it not necessarily lead to or exacerbate a depression. One can be depressed and not sad, or sad and not depressed, or both sad and depressed depending on the person and the circumstances.

    Secondly, there is no one or two neurotransmitters that we can point to and say "those are the chemicals responsible for depression" – we look for balance in relative amounts of neurotransmitters. Deficits may indeed be a problem, but so also can be relative excesses.

    Neurotransmitter testing offers a great deal of valuable information, but must be interpreted very carefully by someone skilled in that assessment.

    You may want to consider a Brief Consultation with Dr. Myatt who can help your understanding of this complex subject.

    Hope this helps,

    Cheers,

    Nurse Mark

     

    Neurotransmitters are just another way of saying “Brain Hormones,” and they are another part of that miraculous, amazing bio-computer that we call the endocrine system. When it comes to questions about neurotransmitters, the very best way to get answers is through a Brief Consultation with Dr. Myatt.