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  • 4 Diet Shootout – And The Winner Is…

    Another round in the ongoing “Diet Wars” goes to Atkins and the Low Carb diet.

     

    By Nurse Mark

     

    It seems the “Diet Wars” might just never end.

     

    There are the veggie eaters who are disgusted by the cavemen meat eaters,
    the whole food and raw food crowds,
    the low fat folks,
    the high carb and the low carb camps,
    the protein lovers and the protein haters,
    the juicers and the squeezers,
    the junk foodies and super-size me’s, and,
    there’s even a bunch that is working valiantly to figure out how they can get all the sustenance they need from sunlight, fresh air, and pure thoughts – who call themselves Breathairians.

    Just like so many opposing viewpoints in today’s world – political, religious, tribal, ethnic, and so on – the chances of these different dietary believers ever acknowledging the worth of any diet but their own are slim-to-none.

    Still, medical researchers continue to take up the cause and try to figure out if there might really be one dietary regimen that is better than all others – I guess it is just human nature to want to classify things as “Good, Better, and Best” or “winner” and “loser.”

    In a study in  called  “Comparison of the Atkins, Zone, Ornish, and LEARN diets for change in weight and related risk factors among overweight premenopausal women: the A TO Z Weight Loss Study: a randomized trial.” done by Stanford University Medical School and published in JAMA in 2007 the researchers looked at 4 popular and relatively “mainstream” diets:

    • The Atkins diet, a very low carbohydrate but liberal fat and protein diet plan,
    • The Zone diet that advocates a “40:30:30” ratio of calories obtained from carbohydrates, proteins, and fats, respectively,
    • The Ornish diet that excludes cholesterol and saturated fat, including all animal products (except egg whites and nonfat dairy products), nuts, seeds, avocados, chocolate, olives, and coconuts and eliminates all oils, and
    • The LEARN (Lifestyle, Exercise, Attitudes, Relationships, and Nutrition) diet that recommends 55% to 60% energy be obtained from carbohydrate and that less than 10% energy come from from saturated fat.

    Three high carbohydrate, low fat diets, put up against one low carbohydrate, high fat diet.

    Just over 300 overweight/obese, nondiabetic, premenopausal women were divided into 4 groups and each group was directed to follow one of the four diet plans for a full year.

    The main thing that the researchers wanted to see was weight loss – but they also looked at what they called “secondary outcomes” which included lipid profile (aka “cholesterol levels”), percentage of body fat, waist-hip ratio, fasting insulin and glucose levels, and blood pressure.

    So, what did they find? (I thought you would never ask…)

    Weight loss for each of the diets at the end of 12 months was:

    • Zone diet – about 3.5 pounds (1.6 kg)
    • Ornish diet – about 4.8 pounds (2.2 kg)
    • LEARN diet – about 5.7 pounds (2.6 kg)

    And finally; (drum roll please…!)

    • Atkins dieters lost about 10.3 pounds (4.7 kg) with weight losses within that group ranging from as “little” as 6.8 pounds to as much as 13.8 pounds!

    And, those “secondary outcomes” that they thought they might check while they were at it?

    The researchers were forced to admit that “At 12 months, secondary outcomes for the Atkins group were comparable with or more favorable than the other diet groups.”

    And finally, the researchers rather grudgingly conclude that “a low-carbohydrate, high-protein, high-fat diet may be considered a feasible alternative recommendation for weight loss.”

    Folks, this is what Dr. Myatt has been telling us for years now. Check out her Super Fast Diet – which actually builds and improves on the success of the Atkins plan with over two decades of Dr. Myatt’s clinical experience and patient successes.

     

    References:

    http://www.ncbi.nlm.nih.gov/pubmed/17341711

  • Statin Drugs Linked To Cataracts

    Cholesterol: So Vital For So Many Things…

     

    By Nurse Mark

     

    A newly published research paper titled “Age-related cataract is associated with type 2 diabetes and statin use” from the School of Optometry at the University of Waterloo in Canada sounds yet another warning about the use of statin drugs to lower cholesterol levels.

    An article in the August 13, 2012 on-line edition of TheHeart.org (a division of WebMD) tells us that researchers have found:

    Statin users are more than 50% likelier to develop age-related cataracts, according to the results of a new study. And type 2 diabetics who use statins are at even greater risk of cataracts, report investigators.

    “The bioplausibility of these results lies in the fact that the crystalline lens membrane requires high cholesterol for proper epithelial cell development and lens transparency,” writes Dr Carolyn Machan (University of Waterloo, ON) and colleagues in the August 2012 issue of Optometry and Vision Science. “Increased cataract formation has been seen in both animals and humans with hereditary cholesterol deficiency, and the risk exists that statins can inhibit cholesterol biosynthesis in the human lens.”

    While this is yet more evidence that statin drugs are a toxic pox perpetrated on modern man by Big Pharma, it is also more evidence that cholesterol is actually our friend and essential to so many vital processes in our bodies that we are foolish to fall for the “lower your cholesterol by any means possible” propaganda that Big Pharma uses to sell their drugs.

    Now to be fair, the heartwire article author sought out comment from Dr Richard Karas of Tufts University School of Medicine who pooh-poohs the research findings, saying: “It’s a nice paper, an interesting observation, and it isn’t alarmist in that it doesn’t make a blanket recommendation that we should start providing screening for all patients undergoing statin therapy,” … “I think it raises the issue where additional study in perhaps an even larger patient population might be warranted. Also, it raises awareness of the potential for an issue, but on its own this study doesn’t confirm that cataracts are an issue.”

    Does this sound like a statement made by someone with an interest in maintaining the sales figures for statin drugs? It turns out that Karas has received honoraria from Merck and Abbot and research support from Pfizer. One would not want to accuse a respected professional of anything unethical, but it might be expected that he would be supportive of someone who is paying his bills – or as they say “He who pays the piper calls the tunes!”

    There you have it – two sides of an argument. One side warns that statins and lowered cholesterol could raise the risk of developing cataracts, the other side says that we mustn’t worry about such things since all of us will develop cataracts eventually anyway, and keeping cholesterol levels as low as possible outweighs any other risks.

    You decide…

     

    References:

    http://www.medscape.com/viewarticle/769077

    http://www.ncbi.nlm.nih.gov/pubmed/22797512?dopt=Abstract

  • Do Eggs Really Cause Blocked Arteries?

    Cholesterol: Found At The Scene Of The Crime – But NOT GUILTY!

     

    By Nurse Mark

     

    We have recently seen breathless headlines in the mainstream media proclaiming eggs to be almost as deadly as cigarettes. Dr. Myatt answered an inquiry from one of her patients about this in her recent HealthBeat News article Eggs As Bad As Smoking: Really?.

    This sensational reporting is in response to a recently published research article titled “Egg yolk consumption and carotid plaque” in which the lead researcher goes to great lengths to establish that eating egg yolks can cause some people to have an increase in plaque formation in their arteries. And as we have been told, incessantly and stridently since the 1950’s, cholesterol plaque buildup in our arteries is not a good thing.

    Still, being told that eating egg yolks is “almost as bad as smoking” is pretty serious and I wanted to know more. You see, I was a smoker many, many years ago, and I do enjoy eggs frequently now.

    It turns out that the lead author of this research paper is David Spence – a Canadian researcher, medical doctor, and university professor who teaches neurological science at University of Western Ontario. He is well-known for his work in using ultrasound to measure plaque build-up in carotid arteries (the big arteries of the neck).

    It also seems that this fellow has been on a vitriolic crusade against cholesterol for many years, publishing paper after paper that essentially tell us that:

    • cholesterol is a poison that must be purged from our bodies by whatever means necessary and,
    • if we would only stop eating cholesterol we would live happily ever after, and,
    • the most evil source of cholesterol known to man is surely the lowly egg yolk.
    • Therefor, we must all stop eating egg yolks or our arteries will fill up with cholesterol and we’ll die.

    (I’m summarizing and paraphrasing a little bit here of course, but that’s the gist of his argument.)

    He has published numerous papers and made several videos to support his argument and his bias against cholesterol and eggs is blatantly obvious.

    In a 2010 interview with TheHeart.org (a division of WebMD) Spence lamented that “The public’s attention is beginning to drift away from the anti-cholesterol message that doctors have been preaching for 40 years” and went on to complain that A widespread misconception has been developing among the Canadian public and among physicians. It is increasingly believed that consumption of dietary cholesterol and egg yolks is harmless.”

    This interview was in regard to his research paper “Dietary cholesterol and egg yolks: Not for patients at risk of vascular disease” that appeared in the Canadian Journal of Cardiology where he goes on to say that an egg has “even more [cholesterol] than some infamous fast-food items such as KFC’s Double Down or Hardee’s Monster Thickburger.”

    Wow – if this is true and if cholesterol is such a poisonous substance I should be able to close my eyes, listen carefully, and just about hear the plaque building up in my carotid arteries…

    Now, while I have never had an ultrasound exam of my carotid arteries done, I do have my cholesterol levels checked regularly – and they are just fine thank you very much, all those eggs notwithstanding.

    So I wondered, how can this be? After all, those fast food items that we mentioned earlier have been called “heart attack on a plate” and if an egg has more of this bad stuff cholesterol than that…

    It turns out that maybe cholesterol isn’t as bad as we are being told. Sure, having big blobs of cholesterol plugging up one’s arteries is not a good thing, but it looks like simply eating foods that contain cholesterol isn’t what makes that happen, and there is plenty of research to back that up.

    Still, Dr. Spence addresses that small inconvenience, saying:

    Epidemiological studies of egg consumption that failed to show a link between eggs and cardiovascular disease in healthy people were not powered to show an effect in healthy people …

    So, if I’m reading that statement correctly, the good doctor feels that if only the studies had been “powered” differently they might have come up with results that made him happier? Is “powered” another way of saying “massage the numbers” or “cook the books”?

    This particular researcher talks a lot like someone who works for Big Pharma – making research and studies say what he wants or needs them to… surely it couldn’t be… nah

    But wait – a disclaimer at the bottom of the 2010 heart.org HeartWire article where he complains about the amounts of cholesterol in eggs has the following to say:

    Spence and coauthor Dr Jean Davignon (Institut de recherches cliniques de Montreal, QC) report honoraria and speaking fees from several manufacturers of lipid-lowering drugs. Davignon has received support for an annual symposium from Pfizer Canada, and his research has been funded by Pfizer Canada, AstraZeneca Canada, and Merck Frosst Canada.

    Hmmm… so maybe his intentions aren’t so pure and academic and altruistic after all… maybe being anti-cholesterol, and promoting the notion that cholesterol must be reduced by whatever means necessary (like drugs?) actually pays pretty well…

    All-righty then, what other information is there out there about cholesterol, and eggs, and blocked arteries?

    It turns out there is plenty – and a lot of that is not going to make the good Doctor Spence happy.

    Dr William Castelli (the director of the Framingham study) said:

    “In Framingham, Massachusetts, the more saturated fat one ate, the more cholesterol one ate, the more calories one ate, the lower people’s serum cholesterol…we found that the people who ate the most cholesterol, ate the most saturated fat, ate the most calories weighed the least and were the most physically active.”
    Source: Castelli, William, “Concerning the Possibility of a Nut. . .” Archives of Internal Medicine, Jul 1992, 152:(7):1371-1372

    And Ancel Keys, a famous researcher who spent decades working to vilify animal fats and cholesterol is said to have made the following statement at the University of Minnesota in 1997:

    “There’s no connection whatsoever between cholesterol in food and cholesterol in the blood, and we’ve known that all along. Cholesterol in the diet doesn’t matter at all unless you happen to be a chicken or a rabbit.”

    This, from the man who invented the military K-ration, popularized the Mediterranean Diet, and achieved academic and medical acclaim for his work on the Starvation Studies and the Seven Countries Study.

    In another study, from Kansas State University titled “Egg phosphatidylcholine decreases the lymphatic absorption of cholesterol in rats” and published in 2001 finds that a chemical present in egg yolk actually reduces the absorption of cholesterol.

    The researcher states:

    “If these findings prove to be applicable in humans, they may explain the fact that, although egg yolk contains high levels of cholesterol (260 mg), consuming one or two eggs per day does not increase blood cholesterol levels and CVD risk. Egg yolk contains high levels of phosphatidylcholine (1.3g), which might significantly lower the intestinal uptake of egg cholesterol in humans as well.”

    Then there is this study: “Regular egg consumption does not increase the risk of stroke and cardiovascular diseases.” done in 2007 by the Epidemiological and Outcomes Research Division, Zeenat Qureshi Stroke Research Center, Department of Neurology and Neurosciences, University of Medicine and Dentistry of New Jersey:

    Consumption of greater than 6 eggs per week (average of 1 egg or greater per day) does not increase the risk of stroke and ischemic stroke. The increased risk of coronary artery disease associated with higher egg consumption among diabetics warrants further investigations.”

    To be fair, the researchers found that there might be increased risk in diabetics. We’ll look more at why this might be in a little bit.

    Let’s look at just one last rat study – though there are plenty more out there. “An egg-enriched diet attenuates plasma lipids and mediates cholesterolmetabolism of high-cholesterol fed rats” was done by the College of Food Science and Technology at Huazhong Agricultural University in China and concludes:

    “…rats fed an egg-enriched diet had lower plasma triglycerides, total cholesterol, low density lipoprotein (LDL)-cholesterol, hepatic triglyceride, and cholesterol concentrations, and greater plasma high-density lipoprotein cholesterol concentration, …than those fed a plain cholesterol diet”

    And one last human study titled “Effects of eggs on plasma lipoproteins in healthy populations” from the Department of Nutritional Sciences at The University of Connecticut in which the author concludes:

    “…dietary recommendations aimed at restricting egg consumption should be taken with caution and not include all individuals. We need to acknowledge that diverse healthy populations experience no risk in developing coronary heart disease by increasing their intake of cholesterol but in contrast, they may have multiple beneficial effects by the inclusion of eggs in their regular diet.”

    Now, you’ll remember that I said, when I briefly discussed the study “Regular egg consumption does not increase the risk of stroke and cardiovascular diseases.” that we would look more at why diabetics might be at higher risk. It turns out that carbohydrates – not fats – might be the real villain in all this atherogenic, artery blocking epidemic.

    Consider this research article from Austria: “The atherogenic potential of dietary carbohydrate

    The author Dr. Wolfgang Kopp concludes:

    High-carbohydrate diets, particularly in the form of high-glycemic index carbohydrate, have the ability to directly induce atherosclerosis. Based on anthropologic facts, the reason for these dietary-induced, insulin-mediated, atherogenic metabolic perturbations are suggested to be an insufficient adaptation to starch and sugars during human evolution. Restriction of insulinogenic food (starch and sugars) may help to prevent the development of atherosclerosis, one of the most common and costliest human diseases.”

    Dr. Kopp is telling us that we are really not very well equipped to digest carbohydrates – our ancestors were better suited to eat fats and proteins.

    Certainly our distant ancestors must have taken great delight in finding a honeybee tree, or fruits in season, or a starchy tuber that they managed to pull from the ground, but they were far more likely to stay alive foraging for birds eggs or bunnies or fish or lizards or whatever other concentrated fat and protein source they could find. It was not until the historically quite recent advent of organized agriculture that starches, breads and other concentrated carbohydrates began to replace ancient man’s high fat, high protein diet, and it should come as no surprise that many of our “diseases of modern civilization” – obesity, diabetes, cardiovascular disease, cancer – began to appear at about that same time.

    So, my recommendation? Go get yourself your favorite “Heart Attack Burger.” Toss away the bun and the fries and enjoy. Lose the oatmeal and pancakes at breakfast – have yourself some ham and eggs. For supper, a nice, thick, juicy steak – hold the baked potato and dinner rolls though – swap them for broccoli with butter and a crispy green salad.

    At the Wellness Club we believe that fats and proteins are not the problem, they are the solution.

    The true villain in our epidemic of diseases of modern civilization is our excessive reliance on carbohydrates as a food source.

    Carbohydrates cause inflammation – especially within our arteries. Our bodies try to heal that inflammation and damage to the inner surface of the arteries (the endothelium) by producing a fibrin/calcium/cholesterol patch, much the same way your skin responds to damage by producing a protective scab. That scab when it is in your artery is called an atherosclerotic plaque and yes, over time it can build up an cause blockage, or break free and cause stroke. And yes, these plaques contain cholesterol.

    But does cholesterol cause atherosclerosis? NO! It is there because it is trying to protect the artery from inflammation.

    It’s at the scene of the crime – but NOT GUILTY!

    Go eat an egg for heaven’s sake!

     

    References:

    Castelli quote – http://archinte.ama-assn.org/cgi/content/summary/152/7/1371

    Ancel Keys info – http://en.wikipedia.org/wiki/Ancel_Keys

    Eggs lower cholesterol absorption – http://www.theheart.org/article/280769.do

    Eggs lower cholesterol absorption – http://www.ncbi.nlm.nih.gov/pubmed/11533279?dopt=Abstract

    Eggs don’t increase risk – http://www.ncbi.nlm.nih.gov/pubmed/17179903?dopt=Abstract

    Egg-enriched diet reduces cholesterol – http://www.ncbi.nlm.nih.gov/pubmed/22234516

    Eggs are beneficial – http://www.ncbi.nlm.nih.gov/pubmed/21776466

    Atherogenic potential of carbohydrate – http://www.ncbi.nlm.nih.gov/pubmed/16540158

    Eggs reduce inflammation caused by carbohydrates – http://www.nutritionandmetabolism.com/content/5/1/6/

  • Eggs As Bad As Smoking: Really?

    Sensational Headline Says Eating Eggs Is “Almost” As Dangerous As Smoking. So, What’s The Truth?

     

    Dr. Myatt answers patient questions – with a forward by Nurse Mark

     

    It seems that a Canadian researcher and professor at the University of Western Ontario by the name of Dr. John David Spence is once again enjoying a few minutes basking in the glow of media attention. In a press release titled “Research finds egg yolks almost as bad as smoking” which discusses a research article by Spence and co-researchers Jenkins and Davignon titled “Egg yolk consumption and carotid plaque” the doctor continues his long-standing crusade against cholesterol, eggs, and egg yolks in particular with a retrospective study that asked participants to remember how many eggs they ate and how many cigarettes they smoked in past years.

    It is no surprise that the press worldwide has seized upon this rather dramatic headline and parroted it in sensational article after sensational article, panicking their readers and leading a number of our HealthBeat News readers to write us to ask for the truth.

    One of those who wrote is a university professor, scientist, and doctor who is also a patient of Dr. Myatt. Since his diet is now The Myatt Diet and liberally includes eggs he was concerned that there might be any basis to this research.

    Here is Dr. Myatt’s answer to Dr. Keith:

     

    Let’s look at this “study.” It wasn’t an intervention study, it was a retrospective, “questionnaire” study.

    That means it is in the same category as “The Rooster Crowing Brings the Sun Up.” Please read here to remind yourself how this works. This is an excellent article if I do say so myself.

    Secondly, other variables were not examined. Do egg yolks really cause atherosclerosis in people consuming a low-carb diet? We don’t know if the remainder of diet composition makes a difference because that wasn’t looked at. Even the authors of the paper you cite state, “this hypothesis should be tested in a prospective study with more detailed information about diet, and other possible confounders such as exercise and waist circumference,” meaning other variables can cloud the issue.

    I submit to you that the remainder of the diet makes a HUGE difference as to whether or not egg yolks or other cholesterol-containing foods have a deleterious effect.

    Fats and cholesterol are not problem foods. They only become so when the diet is high in carbs. It is actually the carbs that are inflammatory and atherogenic. (1-4)

    There’s been a lot of wrong things said about fats including saturated fats.

    The “dietary cholesterol causes high cholesterol” debate is in serious question because the data which “support” this position are inconclusive, spotty and with much conflicting evidence. Read “Saturated Fats: Another Big Fat Lie” to learn more.

    Finally, and not least of all, I have been using a low-carb diet with patients for 23 years now, which has given me the opportunity to observe how health changes including cardio risk factors, diabetes and even cancer. These things always get better when the diet is followed correctly. (Some people claim they are following the diet but an examination of a diet diary can reveal that they are cheating enough so as to be “not doing it”.)

    Remember, for any question, you will find published studies on both sides of an issue. There is almost never “black and white” in medicine or in anything else. So one must consider the preponderance of evidence, and how well-done and interpreted the studies are, and if the researchers had any bias, etc. etc. Just because you find one contrary study about eggs does NOT a “smoking gun” make!

    In case you want to see some evidence on the other side of the equation, here are just a few of the many scientific studies which show that low-carb diets –which typically include eggs “ad libitum” — prevent atherosclerosis and high-carb diets promote atherosclerosis. (see references 4-15)

    And with this current defamation of eggs yolk, I must defend their honor. Egg yolks are chock-full of  “super nutrients” including:

    • lutein and zeaxanthin: two carotenoids which help protect the eyes from cataracts and macular degeneration.
    • choline: a B-vitamin-like essential nutrient needed for structural integrity, cell-signaling and acetylcholine synthesis. Choline is a major source of methyl groups which are are required for liver function, cellular replication, and detoxification reactions.
    • lecithin / phosphatidyl choline: needed for cell membrane integrity and intracellular communication
    • essential fatty acids, vitamins A, E, D, and K, calcium, iron, phosphorus, zinc, thiamin, B6, folate, B12, and panthothenic acid

    Anything else I can clarify for you today? If not, go eat an egg…!!!

    In Health,
    Dr. Myatt

    References

    1.) Torres-Gonzalez M, Shrestha S, Sharman M, Freake HC, Volek JS, Fernandez ML.
    Carbohydrate restriction alters hepatic cholesterol metabolism in guinea pigs fed a hypercholesterolemic diet. J Nutr. 2007 Oct;137(10):2219-23. [Dr. Myatt’s Note: I’m not ordinarily impressed with animal studies but guinea pigs do not produce endogenous vitamin C and neither do humans, making them one of the best experimental animals for human research.]
    2.) Kopp W. The atherogenic potential of dietary carbohydrate.Prev Med. 2006 May;42(5):336-42. Epub 2006 Mar 15.
    3.) Faghihnia N, Tsimikas S, Miller ER, Witztum JL, Krauss RM. Changes in lipoprotein(a), oxidized phospholipids, and LDL subclasses with a low-fat high-carbohydrate diet. J Lipid Res. 2010 Nov;51(11):3324-30. Epub 2010 Aug 16.
    4.) Wood RJ. Effect of dietary carbohydrate restriction with and without weight loss on atherogenic dyslipidemia. Nutr Rev. 2006 Dec;64(12):539-45.
    5.) Feinman RD, Volek JS. Low carbohydrate diets improve atherogenic dyslipidemia even in the absence of weight loss. Nutr Metab (Lond). 2006 Jun 21;3:24.
    6.) Leite JO, DeOgburn R, Ratliff J, Su R, Smyth JA, Volek JS, McGrane MM, Dardik A, Fernandez ML. Low-carbohydrate diets reduce lipid accumulation and arterial inflammation in guinea pigs fed a high-cholesterol diet. Atherosclerosis. 2010 Apr;209(2):442-8. Epub 2009 Oct 12. [Dr. Myatt’s Note: I’m not ordinarily impressed with animal studies but guinea pigs do not produce endogenous vitamin C and neither do humans, making them one of the best experimental animals for beginning human research.]
    7.) Westman EC, Feinman RD, Mavropoulos JC, Vernon MC, Volek JS, Wortman JA, Yancy WS, Phinney SD. Low-carbohydrate nutrition and metabolism. Am J Clin Nutr. 2007 Aug;86(2):276-84.
    8.) Volek JS, Fernandez ML, Feinman RD, Phinney SD. Dietary carbohydrate restriction induces a unique metabolic state positively affecting atherogenic dyslipidemia, fatty acid partitioning, and metabolic syndrome. Prog Lipid Res. 2008 Sep;47(5):307-18. Epub 2008 Mar 15.
    9.) Adam-Perrot A, Clifton P, Brouns F. Low-carbohydrate diets: nutritional and physiological aspects. Obes Rev. 2006 Feb;7(1):49-58.
    10.) Brehm BJ, Seeley RJ, Daniels SR, D’Alessio DA. A randomized trial comparing a very low carbohydrate diet and a calorie-restricted low fat diet on body weight and cardiovascular risk factors in healthy women. J Clin Endocrinol Metab. 2003 Apr;88(4):1617-23.
    11.) Gardner CD, Kiazand A, Alhassan S, Kim S, Stafford RS, Balise RR, Kraemer HC, King AC. Comparison of the Atkins, Zone, Ornish, and LEARN diets for change in weight and related risk factors among overweight premenopausal women: the A TO Z Weight Loss Study: a randomized trial. JAMA. 2007 Mar 7;297(9):969-77.
    12.) Grieb P, Klapcinska B, Smol E, Pilis T, Pilis W, Sadowska-Krepa E, Sobczak A, Bartoszewicz Z, Nauman J, Stanczak K, Langfort J. Long-term consumption of a carbohydrate-restricted diet does not induce deleterious metabolic effects. Nutr Res. 2008 Dec;28(12):825-33.
    13.) Kim JY, Yang YH, Kim CN, Lee CE, Kim KI. Effects of very-low-carbohydrate (horsemeat- or beef-based) diets and restricted feeding on weight gain, feed and energy efficiency, as well as serum levels of cholesterol, triacylglycerol, glucose, insulin and ketone bodies in adult rats. Ann Nutr Metab. 2008;53(3-4):260-7. Epub 2009 Jan 9.
    14.) Seshadri P, Samaha FF, Stern L, Chicano KL, Daily DA, Iqbal N. Free fatty acids, insulin resistance, and corrected qt intervals in morbid obesity: effect of weight loss during 6 months with differing dietary interventions. Endocr Pract. 2005 Jul-Aug;11(4):234-9.
    15.) Yancy WS Jr, Olsen MK, Guyton JR, Bakst RP, Westman EC. A low-carbohydrate, ketogenic diet versus a low-fat diet to treat obesity and hyperlipidemia: a randomized, controlled trial. Ann Intern Med. 2004 May 18;140(10):769-77.

  • Diets – What Are They Good For?

    Why Do We Go To All The Trouble And Effort To “Diet”?

     

    Part 2 In A Series By Nurse Mark

     

    In our first “Diet” article we saw that:

    • Everyone is on a “diet” of some sort
    • Some “diets” are followed for moral reasons, others for medical reasons.
    • The food intake of our “diet” provides us with energy – measured as “calories”
    • Of the three food types that we consume for energy, only two are “essential” to life (pop quiz: which two?)

    And now we’ll look at some common physical conditions and how those conditions affect our dietary needs. Next, we’ll look at some of the more trendy or popular diets with some thoughts on their strengths, weaknesses, and even dangers. We’ll also look at vitamins, minerals, and micronutrients to see how and where they fit into the dietary picture. Finally, we’ll look at how to put all this knowledge together and look at Nutrition Facts Boxes on foods so that we can make better dietary decisions.

    Some of the physical or medical conditions that cause people to alter, modify, manage, or otherwise control their food intake include:

    • Obesity
    • Cardiovascular disease – including hypercholesterolemia (high cholesterol) and hypertension (high blood pressure)
    • Food allergies, sensitivities, and intolerance
    • People with inherited metabolic disorders, such as PKU and Homocystinuria or with kidney or liver disease may be prescribed a low protein diet.
    • Neurological disorders such as epilepsy, ALS, bipolar disorder, depression, autism, and more often respond dramatically to dietary changes.
    • Diabetes
    • Cancer
    • Weight gain may be desired for any number of reasons from increased athletic performance to recovery from illness to pregnancy.

    Let’s look at these a little more closely, and at some of the dietary strategies that are proposed for each.

    Obesity and overweight are the first condition that most people think of when they hear the word “diet.”  In it’s most basic terms, overweight and obesity is a result of consuming more energy (food) than the body requires. The excess is stored as fat, an evolutionary adaptation that allowed early man to survive lean times. In today’s context however things are not so simple.

    We have access to foods that are far more calorie-dense than our distant ancestors could dream of – in the form of sugars and other concentrated carbohydrates. Because these foods tend to have less nutritive value than some other, healthier choices, many obese and overweight persons are actually malnourished – lacking in fats, proteins, and micronutrients such as vitamins and minerals. They get enough calories to make them fat but not enough nutrients to make them healthy or satiated.

    Here is an essential truth: All “reducing diets” are calorie restriction diets – the differences between the multitude of diets available is in which of the calorie-containing macronutrients are restricted.

    Most (if not all) of the diet plans that win approval of the conventional medical establishment favor some restriction of all three macronutrients – fats, proteins and carbohydrates – usually with special attention given to reducing fats and animal-based proteins while increasing the intake of fruits, vegetables, and “good” carbohydrates such as whole grains and fibers. Not surprisingly, these diets tend to be hardest to adhere to since they rely on deprivation – meal servings must be smaller and thus less satisfying. Ornish is one popular example of this type of diet.

    Others diets reduce caloric intake by restricting carbohydrates while allowing nearly unlimited proteins and fats. While they do not initially seem to be diets of deprivation many people find that they crave carbohydrates such as breads and starches and sweets and complain that the diets are “boring” and “monotonous” because of that. While the nearly unlimited allowances of fats and animal protein make diets like the Atkins diet satisfying and nutritionally complete the restriction of sweets and carbohydrates can lead to dissatisfaction and surprisingly, excessive protein intake can result in weight (fat) gain through gluconeogenesis – effectively undermining the dieters efforts.

    A variety of other weight loss diets all promote themselves as being the best and range from mixed macronutrient diets relying on portion control such as The South Beach Diet to radical fasts and semi fasting diets that rely on near complete food deprivation such as grapefruit or cabbage soup or water fast schemes. There are also diet plans that rely on “gimmicks” such as the HCG diet which uses injections of small doses of HCG (Human Chorionic Gonadotropin) as an adjunct to a very low calorie deprivation diet plan, or the various commercial diets that rely on special prepackaged foods or “meal replacements.”

    All potential weight-loss diets must be evaluated on their nutritional completeness, for any diet that lacks in essential nutrients has the potential to cause significant malnutrition and ill health and can lead to rebound weight gain.

    Cardiovascular disease, including high blood pressure and high cholesterol, is another condition for which conventional medical wisdom will prescribe diets – usually low-fat, low-salt, low protein, and high in “low glycemic index” carbohydrates, along with the usual mantra of “more fresh fruit and vegetables.” Unfortunately these conventional recommendations usually do little more than make the dieter miserable, and often make the medical condition worse.

    While diets like the Pritikin and Ornish have some success if very carefully adhered to there is evidence that a Very Low Carbohydrate diet that allows adequate fat and protein can be highly effective and easier to stick with. Cholesterol control is paradoxically easier to achieve on a diet of adequate fats and protein and restricted carbohydrates than by attempts to limit dietary cholesterol – since the liver is quite effective at creating this vital substance de novo (from new, or by itself). Blood pressure control becomes much easier when carbohydrates are limited – salt limitation is effective in only a small percentage of patients and carbohydrates cause as much or more water retention than salt.

    Diabetes and “Metabolic Syndrome” diets as prescribed by conventional medical and dietetic practitioners tend to look very much like conventional weight loss and conventional cardiovascular diets – that is, the standard recommendation as promoted by the A.D.A. (American Diabetes Association) and others is usually low-fat, low-salt, low animal protein, and high in “low glycemic index” carbohydrates, along with the usual “more fresh fruit and vegetables.”

    Because these diets tend to be carbohydrate based, dieters have difficulty actually reversing the condition and the best that can be hoped for is usually “stabilization” of blood sugar levels at some arbitrary (and achievable) level so as to allow for safe administration of hypoglycemic drugs or even insulin – based on frequent blood sugar level testing.

    Though still actively discouraged by most conventional dieticians and medical practitioners, the Very Low Carbohydrate (VLCD) diet is well-proven to reverse type II diabetes safely and quickly and is beginning to find some support among practitioners who are willing to look outside of the standard A.D.A. dietary protocols.

    Cancer is a word that terrifies most people, and for every diagnosis of cancer there are dozens of well-meaning family, friends, neighbors, co-workers, and casual acquaintances who all seem to have a theory about the best diet for the disease, and are insistent that the sufferer should “give it a try.”

    Most conventional medical practitioners on the other hand are loathe to concede that diet could play much, if any role in cancer. Other than the standard mantra of “eat more fresh fruit and vegetables” the usual conventional dietary recommendations center around preventing any weight loss during the course of the disease. To this end, high carbohydrate foods and supplements such as Ensure drinks are usually recommended.

    There is also a massive amount of conflicting and often confusing diet advice for cancer on the internet and patients can become overwhelmed, flitting from one promising dietary protocol to another in their search for the curative answer. Much of this advice is based on legend, “common sense” armchair theory, or testimonial rather than science and most of it is wrong – even harmful.

    Even cancer diet advice that is based on science and clinical trial must be evaluated carefully since cancer is not one single disease and the best diet for one cancer may not be appropriate for another.

    Long-dismissed by conventional dietary wisdom as “dangerous,” a ketogenic diet is beginning to find acceptance among more open-minded cancer treatment practitioners. Treatment successes with a Ketogenic diet are often nothing short of spectacular, and medical researchers are beginning to take notice of this dietary strategy that targets a metabolic weakness of most cancer cells.

    Dr. Myatt has been using the Ketogenic diet successfully in her practice for many years and considers it to be an indispensable tool in the treatment of cancer. She has written and teaches on the use of it for many conditions including cancer – more information can be found here: Dietary Ketosis In The Treatment of Solid Tissue Malignancy

    Food allergies, sensitivities, and intolerance are the subject of almost as many special dietary strategies as is cancer, and results that are just as varied.

    Some conditions, like celiac disease are straight-forward: A diet which avoids the protein gluten which is found in barley, rye and wheat is the accepted treatment. For someone with celiac-like symptoms, confirmatory testing can be performed quickly and easily at home with a Celiac / Gluten-Gliaden Sensitivity Panel .

    Other complaints are less cut-and-dried and without extensive testing to determine the true cause of a food-caused gastrointestinal upset sufferers can spend years, even decades in pursuit of an offending food. What seems to cause an allergic reaction at one meal may or may not be the true culprit, and many people deprive themselves of important nutrition by eliminating one food after another from their diet. For these people food allergy and sensitivity testing can save untold misery. Performed at home, a Food Intolerance Profile can provide valuable answers quickly and easily.

    It is also worth remembering that not all “allergies” and “intolerances” are permanent. With careful management intestinal complaints that are sometimes incorrectly attributed to “allergies” can be made to go away and never return.

    Neurological disorders such as epilepsy, ALS, bipolar disorder, depression, autism can all be addressed with diet. Some of the diets, such as the Ketogenic diet for childhood epilepsy have a long and successful history of use (prior to falling into disfavor with the introduction of “anti-seizure” drugs) while other diets claim success by reducing sugars and simple carbohydrates, eliminating food preservatives, colorings, and other synthetic additives, or avoiding stimulants such as caffeine.

    While diet is not well accepted as being a factor in ADD/ADHD by conventional medicine there are legions of mothers of hyperactive children who will disagree and who have excellent results with variations of low carbohydrate diets. Others have found that food allergies play a significant role in abnormal behaviors. In children the Food Intolerance Profile can help isolate food allergies that may be causing behavioral problems.

    While depression is acknowledged by conventional medicine to be a result of certain forms of malnutrition, is rarely addressed through diet by conventional practitioners who rely instead on drug treatments. Bipolar disorder, anxiety disorders, alcoholism, and a variety of other neurological and psychiatric disorders have been successfully addressed with diet, especially low-carbohydrate diets rich in essential fatty acids which serve as precursors to vital neurotransmitters.

    Pregnancy and weight gain are also reasons for manipulating diet – with athletes and body-builders seeking to improve endurance and build muscle mass, and women in pregnancy following the old adage that they are “eating for two.” Recovery from illness or injury often involves weight restoration as well.

    Conventional dietary advice for all these circumstances is usually to follow a diet rich in carbohydrates. This usually does have the effect of rapidly adding weight, but the weight gain is usually that of fluid and fat mass rather than healthy lean muscle. Remember, the body requires protein to build muscle – not carbohydrates. Carbohydrates are useful as a source of energy but contribute nothing more than that. Essential fatty acids and essential amino acids are required in abundance if any tissue building is to be done.

    The stated requirements for increased dietary intake during pregnancy vary from source to source – each “expert” having a slightly different opinion. An overall energy increase of from 200 to 300 Kcal is usually recommended, but mostly during the last trimester of pregnancy.

    Proteins (essential amino acids) must be available in abundance to provide for the formation of a healthy placenta and fetus and to prevent sacrifice of maternal protein (muscle mass) to the developing fetus.

    Essential fatty acids play a vital role in many functions both maternal and fetal. Omega-3 fatty acids increase blood flow to reproductive organs and help regulate reproductive hormones. Consumption is also known to help prevent premature delivery and low birth weight. Other essential fatty acids play a role in brain and nervous system development.

    In addition to increased intakes of the essential macronutrients (fats and proteins) micronutrients must be adequate or fetal development and health will suffer. Folate is one of the better known of the micronutrients since a deficiency can lead to neural tube defects and other serious problems.

    Inflammation reduction is often given as a reason for following special diet regimens. An anti inflammation diet usually restricts refined carbohydrates – foods that elevate insulin and glucose levels, and raise levels of pro-inflammatory cytokines (chemical messengers). Also restricted are Omega 6 fatty acids which are inflammatory. Omega 3 and Omega 9 fatty acids as found in fish oil and olive oil are anti inflammatory and are encouraged. Fresh fruits and vegetables are encouraged for their inflammation-reducing antioxidants and organically raised meats and eggs are encouraged as protein sources. Trans fats are highly inflammatory and are prohibited in this diet. Anti inflammatory herbs and spices such as oregano, rosemary, ginger, turmeric and green tea contain bioflavonoids and polyphenols which reduce inflammation and limit the production of free radicals. Also, remember that any food that causes an allergic or intolerance reaction will be causing inflammation too – so Food Intolerance Profile testing for allergens is very helpful.

    In Summary…

    • Everyone is on a “diet” of some sort (since diet means “way of life”)
    • Some “diets” are followed for moral reasons, others for medical reasons.
    • The food intake of our “diet” provides us with energy – measured as “calories”
    • Of the three food types that we consume for energy, only two are “essential” to life (proteins and fats)
    • Almost every medical condition will respond to changes in dietary intake – many responding dramatically
    • Conventional doctors and dieticians tend to favor diets low in fats and animal proteins and higher in “good” carbohydrates, even though proof for this is scant and conflicting
    • A growing number of practitioners are recognizing that traditional dietary advice may be flawed and that diets that feature lowered carbohydrate intake and increased protein and fats are safe and highly effective for many conditions
    • While fats and proteins are essential nutrients, carbohydrates are not – and they contribute to inflammation
    • Food allergies are common, but not necessarily life-long

    Next, we’ll look at some of the more trendy or popular diets with some thoughts on their strengths, weaknesses, and even dangers. We’ll also look at vitamins, minerals, and micronutrients to see how and where they fit into the dietary picture. Finally, we’ll look at how to put all this knowledge together and look at Nutrition Facts Boxes on foods so that we can make better dietary decisions.

     

    References

    1. Zhao Z, Lange DJ , Voustianiouk A, et al. A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis.BMC Neuroscience 2006, 7:29. (PMID 16584562).
    2. Ketogenic diet to be tested in adults with ALS Medicalpost.com, May 2, 2006
    3. Application of a ketogenic diet in children with autistic behavior: pilot study J Child Neurol. 2003 Feb;18(2):113-8, PMID: 12693778
    4. Ketogenic diet in bipolar illness PMID: 12047499
    5. The ketogenic diet may have mood-stabilizing properties PMID: 11918434
    6. A low-carbohydrate, ketogenic diet to treat type 2 diabetes Nutrition & Metabolism, 1 December 2005
    7. Can a High-Fat Diet Beat Cancer? Time magazine, Sep. 17, 2007
    8. Calorie-restricted diet can fight against cancer? Published in the October 4, 2007 Edition of The Heights
    9. Williamson CS (2006). “Nutrition in pregnancy”. British Nutrition Foundation 31: 28–59.
    10. Leite JO, DeOgburn R, Ratliff J, Su R, Smyth JA, Volek JS, McGrane MM, Dardik A, Fernandez ML. Low-carbohydrate diets reduce lipid accumulation and arterial inflammation in guinea pigs fed a high-cholesterol diet. Atherosclerosis. 2010 Apr;209(2):442-8. Epub 2009 Oct 12